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Water Woes or Water Win? Probing Water Vapor Uptake and Release with Dynamic Vapor Sorption (DVS)

Water Woes or Water Win? Probing Water Vapor Uptake and Release with Dynamic Vapor Sorption (DVS)

By Chorthip Peeraphatdit – Particle Characterization Chemist IV / Team Leader

Water is one of the most important substances on earth, yet it can also be the source of some major headaches throughout the lifecycle of a product. Uptake of moisture from the environment could cause unwanted changes in various materials. If you’ve ever tasted stale chips or seen sugar granules clump up after the package was opened, you’ve had firsthand experience with some of these changes. Understanding how your product might interact with ambient water vapor, how moisture might move between different ingredients, and permeability of the packaging material could help you optimize your process and ensure quality of your product. 

In this article, we’ll focus on one essential tool for studying moisture sorption-desorption process: Dynamic Vapor Sorption (DVS).

What does the DVS technique measure?

Questions about Zeta Potential image

Demystifying Zeta Potential

Confused on what a zeta potential measurement is and when it’s useful? You are not alone. In this helpful Q and A, Laboratory Division Manager Ryan Keefer walks us through the basics of zeta potential, points out factors to consider when measuring, and takes us on a little bit deeper dive into the specifics of measurement. This quick read will help you to know what zeta potential is, how it’s measured and when to use it.

Q: What Is Zeta Potential?

Zeta potential per ISO 13099-1:2021(E)(2017) is defined as “difference in electric potential between that at the slipping plane and that of the bulk liquid.” Simply put, it is the charge that develops at the interface between a solid surface and its liquid medium. This interface is called the Slipping plane.

Why Is Zeta Potential Important? 

The importance of zeta potential is relative to specific industry goals: 

FAQ’s on Gas Adsorption Surface Area Measurements

FAQ’s on Gas Adsorption Surface Area Measurements

Have you found yourself confused about how best to determine the surface area of your sample?  How does the analysis work? What does “BET” mean? How many points do I need to collect? What is the appropriate analysis gas? Here, we offer answers to some of the most frequently asked questions about gas adsorption surface area measurements.

How is surface area determined using gas adsorption?  

 To determine specific surface area, we are measuring the quantity of gas required to form a layer of molecules around the surface of a provided sample. The gas used to cover this sample is referred to as the adsorbate and has a known molecular cross-sectional area. If we can determine the quantity of gas molecules required to encapsulate the surface of the sample, we can use the cross-sectional area of the adsorbate to determine the approximate surface area of the sample.  

Particle Technology Labs Marks 30th Anniversary

Industry Leader Particle Technology Labs Marks 30th Anniversary

Independent Lab Provides Scientific Data for Making Big Decisions

This year marks Particle Technology Labs’ (PTL) 30th anniversary as a premier particle characterization research and advisory company. Founded in March 1992, PTL serves as a trusted advisor to the world's leading pharmaceutical, industrial, public sector, and scientific organizations. 

Richard F. Karuhn, began this Chicago-area independent lab with a single particle counting instrument and a commitment to providing data that would shape his clients’ business decisions. Very soon, environmental, legal, pharmaceutical and government entities relied upon PTL to provide characterization services.

“Particle characterization is a very niche field but it impacts essentially every industry in some way. Behind the scenes, people are looking at the data and making big decisions in many different industries,” notes Particle Technology Labs' William Kopesky, EVP and Director of Analytical Service.

OOS Investigations at the Contract Lab

OOS Investigations at the Contract Lab

Out of specification (OOS) results are bound to occur at a testing laboratory. It is important that your contract lab investigates the unexpected results in a timely and thorough way.

An OOS result occurs when an analytical result does not meet the applicable specifications. As a cGMP compliant and ISO 17025:2017 accredited laboratory, Particle Technology Labs has established procedures dictating the actions to take upon the discovery of an unexpected result. PTL’s investigation procedures follow the FDA’s Guidance for Industry, Investigating Out-of-Specification (OOS) Test Results for Pharmaceutical Production (2006). The investigation process is initiated whenever an OOS test result is obtained for cGMP or ISO17025 compliant analyses. The purpose of the OOS investigation at PTL is to determine if the result was caused by the measurement process or if it genuinely represents the provided sample.