Analytical Contract Lab Providing Particle Size and Characterization Testing Services

(630) 969-2703


Industries Served - Particle Technology Labs

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PTL is recognized by the U.S. pharma industry as an expert in the field of particle characterization. Not only do we perform thousands of individual analyses, but many particle characterization methods and techniques are developed and validated for our pharma clients each year.

Pharmaceutical companies use particle characterization testing for a wide variety of applications. From the development of active ingredients to problem-solving in the manufacturing process, pharma makes up the largest group of clientele in our laboratory.

One example is drug formulation: the careful blending and processing of precisely specified and measured components to create a final product that delivers the required clinical dose. Particle size distribution, shape, porosity, and surface area are all used in the formulation and manufacturing of drugs.

Particle size distribution has a significant effect on the performance of a drug. The stability, aesthetics, rate of absorption and bioavailability are strongly affected by the size of the particles that comprise the powder or dispersion. Regulatory agencies are aware of the importance of particle size distribution, requiring drug developers to have greater control and understanding of the physical characteristics of their drug products.

Particle Shape is measured to increase understanding and control of manufacturing processes. While two particles may be the same size, their shape may differ, impacting behavior or performance. Particle shape can detect problems during powder flow or particle abrasion. Characterization results can lead to better development of drugs in the pharmaceutical industry.

Surface area and porosity are important factors in the purification, processing, tableting and packaging of pharmaceutical products as well as the drug’s useful shelf-life, its dissolution rate and bioavailability. The surface area of a drug provides information regarding the dissolution rate and other physical parameters.

Examples of pharmaceutical materials we have analyzed include:

  • Active Pharmaceutical Ingredients (API's)
  • Emulsions
  • Excipients
  • Injections
  • Lotions and creams
  • Powders
  • Solid dosage forms
  • Suspensions
  • Topical ointments

This is only a small representation of the material types we have analyzed for the pharmaceutical industry.

Please contact us with any questions or click here to fill out a quote request form for all of your particle characterization needs. We look forward to hearing from you.