Laser Diffraction (also known as Static Light Scattering) is one of the most widely used particle sizing distribution techniques. Samples, which can be analyzed either as a liquid suspension or a dry dispersion, are passed through a laser beam, scattering the light. Detectors placed at fixed angles measure the intensity of light scattered at each position, and a mathematical model (Mie or Fraunhoffer Theory) is then applied to generate a particle size distribution. The final result is reported on an Equivalent Spherical Diameter Volume basis.
Particle Size by Laser Diffraction is recognized by numerous standards and guidance agencies, including the ISO, ASTM, USP, EP and JP. This technique’s ability to perform dry or liquid dispersion analyses make it a good choice for general particle sizing applications, and its broad dynamic range (submicron to millimeters) has proven useful to industries including environmental, pharmaceutical, food, health, and beauty industries.
A wide variety of sample types can be analyzed by Laser Diffraction, including active pharmaceuticals (APIs), excipients, flyash, turbid wastewater, and environmental emission samples. Common applications include QA/QC batch testing, general survey screening measurements, and comparative studies.
Below are the Laser Diffraction Testing instruments PTL utilizes on a daily basis. Please give us a call to discuss how Laser Diffraction might be applied to your samples.