Category Archives: Press

PTL ISO/IEC 17025:2017 Accreditation Complete

Particle Technology Labs, the premier particle characterization service laboratory and advisory company is pleased to announce a change in accreditation status from ISO/IEC 17025:2005 to the most updated ISO/IEC 17025:2017 criteria. From the website, “In order to reflect the latest changes in market conditions and technology, the new edition of the standard encompasses the activities and new ways of working of laboratories today. It covers technical changes, vocabulary and developments in IT techniques and takes into consideration the latest version of ISO 9001 on quality management.”
ISO/IEC 17025 is an internationally recognized quality standard for calibration and testing laboratories. Accreditation to this standard asserts that the laboratory is competent to conduct specific testing as detailed on the certificate of accreditation. For an organization to be ISO 17025 accredited, its facility must undergo a rigorous independent assessment which evaluates the quality management system, training practices, testing programs, and instrument maintenance processes.
This accreditation assures PTL customers that laboratory operations, personnel training, equipment calibration, maintenance, and operation and quality assurance systems are in compliance with ISO/IEC 17025:2017 requirements.
“Particle Technology Labs is dedicated to providing the highest quality service to our customers. One way that we do this is to continually improve and build upon our laboratory practices and quality systems. Securing this accreditation is only a part of the commitment that we keep to our customers, providing the best value and highest standards in particle characterization services.” 
– Richard J. Karuhn, President

The International Organization for Standardization (ISO) is an independent, non-governmental international organization that provides “requirements, specifications, guidelines or characteristics that can be used to ensure that materials, products, and services are fit for their purpose.”(1)  To visit ISO online, click here:
Particle Technology Labs is a proven cGMP (current Good Manufacturing Practices) compliant laboratory, in accordance with 21 CFR, Part 210 and 211. Our facility is FDA registered and inspected, and we host over 30 audits per year from the world’s largest pharmaceutical companies. We are DEA licensed and approved to handle Schedule II through V controlled substances. We also maintain an ATF permit for analyzing pyrotechnics. To visit Particle Technology Labs online, click here:
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Particle Technology Labs Earns Better Business Bureau Accreditation


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Becoming an Accredited Business with the Better Business Bureau is an honor not accorded to all businesses; because not all businesses meet eligibility standards. Particle Technology Labs is pleased to announce today that it has met all BBB standards and is now an Accredited Business.

“Accreditation in the BBB is by invitation only,” says Steve J. Bernas, president & CEO of the Better Business Bureau serving Chicago and Northern Illinois. “And only those businesses that meet our high standards, and pass the review process are approved by our Board of Directors.”

As with all businesses that are accredited by the BBB, Particle Technology Labs has committed to the BBB Code of Business Practices.  The Code is a comprehensive set of policies, procedures and best practices on how businesses treat consumers. These standards call for building trust, embodying integrity, advertising honestly and being truthful. Bernas adds, “To maintain their Accreditation a business must be transparent, honor their promises, be responsive to their customers, and safeguard their privacy.”

“We are proud to be a BBB Accredited Business,” said Richard J. Karuhn, President and CEO of Particle Technology Labs. “From its inception, PTL has been committed to excellence in particle characterization while providing outstanding customer service to each and every one of our clients. Our achieving BBB Accreditation exemplifies that goal.”

Particle Technology Labs has been in business for 27 years offering businesses the best in particle size and characterization contract laboratory services. “We are a values-driven organization.  To us, this means continuously delivering business value to our clients by providing comprehensive and innovative solutions, excellent customer service, expert knowledge in the field of particle technology, and a commitment to analytical integrity,” said Richard J. Karuhn.

For more information, please visit us online at, or phone us at (630) 969-2703.  

About the Better Business Bureau: As a private, non-profit organization, the purpose of the Better Business Bureau is to promote an ethical marketplace. BBBs help resolve buyer/seller complaints by means of conciliation, mediation and arbitration. BBBs also review advertising claims, online business practices and charitable organizations. BBBs develop and issue reports on businesses and nonprofit organizations and encourage people to check out a company or charity before making a purchase or donation.

PTL Now Conducting Analyses for Hemp Derived CBD Oil and Emulsions Containing ≤0.3% THC












Particle Technology Labs is now conducting analyses for hemp derived CBD oil and emulsions containing ≤0.3% THC.

Bioavailability, efficacy, and stability are just some characteristics of food and drug formulations that are attributed to specific particle size. At PTL, dynamic light scattering, nanoparticle tracking analysis, and zeta potential are characterization techniques being used to determine particle size and stability in CBD products, specifically those in the nanoparticle range.

For more information, or a quotation for particle analysis on CBD or other material, please contact us.

Particle Technology Labs Announces the Installation of our Newest Image Analysis Instrument, the Malvern Morphologi 4-ID

Particle Technology Labs announces the installation of our newest image analysis instrument, the Malvern Morphologi 4-ID. This instrument will provide the same advanced particle size and shape image analysis as our G3S, however the 4-ID has the added capability to chemically identify particles using Morphologically Directed Raman Spectroscopy (MDRS).

For more information, click here.

PTL’s Executive Vice President and Director of Analytical Services William K. Kopesky to Present at Malvern Panalytical’s Virtual Laser Diffraction User Meeting

Particle Technology Labs’ Executive Vice President and Director of Analytical Services William K. Kopesky has been invited to be a presenter at Malvern Panalytical’s upcoming Virtual Laser Diffraction User Meeting.

The meeting will be live streamed on February 20th, 2019 from 12:00 pm to 3:00 pm CST. This virtual meeting is an initiative by Malvern Panalytical to “foster the diffusion of knowledge and experience between our support team and those researchers that regularly evaluate particle size data from the Mastersizer.” The three-hour presentation will include a panel of experts along with Q&A session for issues, suggestions, improvement, and feedback regarding Mastersizer laser diffraction instrumentation. For those unable to join the live session, the meeting will be recorded.

For more information regarding this meeting, visit…/S190220LaserDiffractio….

To view PTL’s laser diffraction and other particle size and characterization services, please visit

PTL Adds New Nanoparticle Analyzer, Spectradynes nCS1

In partnership with Spectradyne LLC, Particle Technology Labs has added a new nanoparticle analyzer, Spectradyne’s nCS1, to our particle size and characterization testing services.

Particles are measured using Microfluidic Resistive Pulse Sensing (MRPS), an extension of the well-known Coulter Principle. This method, which is electrical in nature, does not rely on an optical index contrast to distinguish particles from their suspending medium; it is therefore truly orthogonal to light scattering-based techniques. MRPS measures every particle individually, has a higher sensitivity for size and concentration, and can measure a wide concentration range. The technique uses a very small sample volume, approximately 3 μL. This makes it ideal for expensive or limited sample quantities or for an orthogonal measurement of samples already being analyzed at PTL.

From the manufacturer: “Spectradyne’s nCS1 measures individual nanoparticles while accumulating statistically-reliable distributions of particle sizes with quantitative concentration information. This unique capability separates the nCS1 from other technologies such as Nanoparticle Tracking Analysis (NTA) or Dynamic Light Scattering (DLS).”

Nanoparticles are used in cosmetics, food, pharmaceuticals and more, and as the nCS1 is able to accurately measure particles of any type, the instrument has a wide variety of applications for differing client needs. The nCS1 is also rising to prominence in the testing of exosomes, which are an active area of research for the treatment of cancer and other illnesses.

For more information about nanoparticle analysis or a quotation for services, please call us at (630) 969-2703, email, or visit us online at

Key Features of the nCS1 include:

  • – High resolution size and concentration measurements of particles from 50 nm to 10 μm in diameter
  • – Concentration range: approx. 105 to 1012 particles/mL
  • – Disposable microfluidic cartridges that avoid cross-contamination
  • – Max particle detection rate: approx. 10,000 particles/second
  • – Small sample volume required: only 3 μL
  • – Nanoparticles of any material type (transparent & opaque, conducting & insulating)

Particle Technology Labs’ Director of Analytical Services to Give Presentation in Amsterdam

Particle Technology Labs’ Executive Vice President and Director of Analytical Services William K. Kopesky will return to the Netherlands where he will present at The Center for Professional Advancement’s course entitled, Powders: Their Properties and Processing. This is Mr. Kopesky’s second consecutive year presenting. The three-day event will take place December 3rd through December 5th, 2018, in Amsterdam. Other presenters include Dr. Cecil W. Propst and Mr. Dilip Parikh. 
The primary purpose of the course is to “review the various properties of powdered solids pertinent to the development and manufacture of the products of the pharmaceutical, cosmetic and allied industries.”  While the course is designed for those in product development, the event is attended by scientists, suppliers and technologists. The full course description for his presentation can be viewed here.
Joining PTL as a Particle Characterization Chemist in 2000, Mr. Kopesky became Laboratory Manager in 2002 before being named Managing Director in 2008 and Director of Analytical Services in 2012. His years at PTL have given him exposure to a tremendous variety of particle characterization topics, techniques, and projects spanning many industries including pharmaceutical, nutraceutical, environmental, industrial, and more. During his career with PTL, he has conducted presentations and training in the field of particle characterization, provided testimony for patent infringement cases, and has been involved with consulting services in addition to hands-on analytical work.
The Center for Professional Advancement – CfPA is the largest accredited technical training organization in the world offering technical training and continuing professional education courses to those in the pharmaceutical, biotechnology, medical device, chemical engineering and cosmetics industries.

PTL Receives ACIL Customer Quality Service Award

The American Council for Independent Laboratories (ACIL) has announced Particle Technology Labs as one of only 12 recipients of the ACIL Customer Quality Service Award for 2018. This is PTL’s sixth consecutive year in qualifying for this award.

The ACIL Customer Quality Service award program was developed in 1996 to recognize laboratories with exemplary quality performance. This program provides users with a mechanism for evaluating testing laboratories.  Participants are committed to ensuring the integrity of data, meeting customer’s quality needs and setting the standards of performance for the testing laboratory industry.

To participate in the program, laboratories must distribute satisfaction surveys to customers, maintain proof of an annual ethics-training program and an early detection system for questionable analytical practices, and submit a signed code of ethics. The Customer Quality Service Award participants demonstrate that they are proud of the quality they achieve and always operate with customer service as a top priority.

We are pleased to once again successfully qualify into this program. Thank you to all our customers who provided honest feedback regarding our particle characterization services.

For more information about this award, or for any of the services offered at PTL, please visit our website at or contact us at 630-969-2703.


Some comments from our customer satisfaction surveys include:

“Great laboratory. A pleasure to work with.”

“PTL has worked hard with us to resolve issues/investigations expediently and great customer service.”

“We have nothing but top notch service from PTL.”

“We appreciate PTL’s level of confidence, solid expertise, professionalism, honesty and close relationship with customers.”

PTL Installs New Humidity Chamber for Pre-analysis Conditioning

During the course of manufacturing, packaging, storage, or transportation, materials are often exposed to a variety of environmental factors, including differences in temperature and humidity. These changes can affect materials in ways which may impact the quality, reliability, or shelf life of a product or ingredient. To mimic these factors, PTL has installed a Memmert HCP108 humidity chamber.

By pre-conditioning sample material in this humidity chamber prior to analysis, PTL can replicate specific environmental conditions to troubleshoot material issues or conduct comparison studies. Sample material is placed into the chamber and held at a controlled level based on client-provided time, temperature, and humidity specifications. The temperature range can be set from 35°C to 90°C and the humidity range from 20%RH to 95%RH. The unit is computer controlled allowing for ramping and cycling of the temperature and humidity at a specified rate.

Storage conditions can be of specific interest when bulk powder properties appear to change between manufacturing locations or production batches. Powder flowability, bulk/tap density and angle of repose are examples of bulk powder properties typically affected by temperature and humidity during storage. PTL can test for these properties in our laboratory. Storage conditions can also cause different polymorphic forms in pharmaceuticals which can be investigated by using differential scanning calorimetry (DSC). All of these tests are available at PTL.

To find out more about pre-conditioning sample material before analysis, contact us at (630) 969-2703 or online by clicking here.

PTO ISO/IEC 17025:2005 Accreditation



Particle Technology Labs is pleased to announce its new ISO/IEC 17025:2005 accreditation status. This accreditation assures PTL customers that laboratory operations, personnel training, equipment calibration, maintenance, and operation and quality assurance systems are in compliance with ISO/IEC 17025:2005 requirements. For more information and a link to our full accreditation certificate, visit

ISO/IEC 17025 is an internationally recognized quality standard for calibration and testing laboratories. Accreditation to this standard asserts that the laboratory is competent to conduct specific testing as detailed on the certificate of accreditation. For an organization to be ISO 17025 accredited, its facility must undergo a rigorous independent assessment which evaluates the quality management system, training practices, testing programs, and instrument maintenance processes.