Particle Size Distribution Analyses

Laser Diffraction

Particle Size Distribution Analyses - Laser Diffraction

$laser_diffraction$ Laser Diffraction, also known as Static Light Scattering, has become one of the most widely used particle sizing distribution techniques across various industries. Samples can be analyzed on either a liquid suspension or dry dispersion basis. The sample material is passed through a laser beam which results in the laser light scattered at a wide range of angles. Detectors placed at fixed angles measure the intensity of light scattered at that position. A mathematical model (Mie or Fraunhoffer Theory) is then applied to generate a particle size distribution. The final result is reported on an Equivalent Spherical Diameter Volume basis.

Particle Size by Laser Diffraction is widely recognized by numerous standards and guidance agencies such as the ISO, ASTM, USP, EP and JP. This technique’s ability to perform dry or liquid dispersion analyses make it a good choice for general particle sizing applications and its broad dynamic range (submicron to millimeters) has proven useful to the environmental, pharmaceutical, food, health, beauty and many other industries.

A wide variety of sample types are applicable to analysis by Laser Diffraction including active pharmaceuticals (APIs), excipients, flyash, turbid wastewater, and environmental emission samples. Common applications include QA/QC batch testing, general survey screening measurements and comparative studies.

Below are the Laser Diffraction instruments PTL utilizes on a daily basis. Please give us a call to discuss how Laser Diffraction might be applied to your samples…

Malvern Mastersizer S & 2000 - Wet & Dry Dispersion Modules
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Beckman Coulter LS13 320 - Wet & Dry Dispersion Modules
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Microtrac X-100 – Wet Module
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Click here to request a quote or for more information on Laser Diffraction particle testing.

Industries Served

Abrasives Serving the abrasive industry over the last 2 decades, the most common testing performed for this field is particle size and shape analysis. The world of abrasives can encompass a host of varying...
Dietary Supplements Concurrent with the U.S. Food and Drug Administration’s final rule establishing regulations to require current good manufacturing practices (cGMPs) for dietary supplements, PTL can offer cGMP services...
Environmental Testing Services Particle size, particle concentration and other physical characterization analyses are critical to many environmental applications. Regulatory agencies in the environmental sphere demand strict compliance...
Medical Devices Advances in biomedical implant and device technology continue to present new challenges in the area of physical testing. Particle Size Distribution, Surface Area and Porosity measurement data are...
Pharmaceutical Testing Services Supporting drug development with pharmaceutical testing is some of the most exciting work we do. As a premier cGMP contract service laboratory, PTL partners with pharmaceutical scientists to identify...
Beauty / Cosmetics Testing PTL’s analytical staff has years of experience designing test methods and performing analysis for cosmetic, skin care, fragrance and personal hygiene samples. Whether your company needs a third...