Particle Size Distribution Analyses

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A Particle Size Distribution analysis (PSD) is a measurement designed to determine and report information about the size and range of a set of particles representative of a material. Particle size and distribution analysis of a sample can be performed using a variety of techniques, each with advantages and disadvantages, depending on the sample properties and question at hand.

Knowing and controlling the particle size distribution of the primary particles and/or agglomerates present in a material is of utmost importance for research, product development, processing, handling, packaging and quality control. The number of standard organizations and regulatory agencies who have current particle size distribution guidance documents and/or specification requirements is a clear indication of the importance of this information.

Particle Size Distribution is usually expressed from the technique by which it is determined. Particle Technology Labs (PTL) uses a variety of different techniques in order to produce the most accurate particle size analysis possible, based on sample characteristics and the analytical question asked. Many factors influence the choice of technique such as detection limits, particle size range, sample presentation, sample concentration, solubility, particle shape, etc. Our many years of experience and vast array of analytical techniques employed allow PTL to consult with the client to determine the best technique for his or her exact needs. This experience also includes proper techniques for sampling as well as sample preparation in order to achieve accurate and precise results.

At PTL, we can also assist with routine particle distribution release testing using established methods provided by the client. In these cases, companies find that it is often advantageous to use an independent, regulated laboratory, such as PTL, that provides additional insight, feedback and confirmation not always available with in-house testing.

Particle Size Distribution determination has been used extensively to monitor, control, and investigate material properties in countless industries. See the menu links on left to read more about any individual PSD technique offered at PTL.

Industries Served

Abrasives Serving the abrasive industry over the last 2 decades, the most common testing performed for this field is particle size and shape analysis. The world of abrasives can encompass a host of varying...
Dietary Supplements Concurrent with the U.S. Food and Drug Administration’s final rule establishing regulations to require current good manufacturing practices (cGMPs) for dietary supplements, PTL can offer cGMP services...
Environmental Testing Services Particle size, particle concentration and other physical characterization analyses are critical to many environmental applications. Regulatory agencies in the environmental sphere demand strict compliance...
Medical Devices Advances in biomedical implant and device technology continue to present new challenges in the area of physical testing. Particle Size Distribution, Surface Area and Porosity measurement data are...
Pharmaceutical Testing Services Supporting drug development with pharmaceutical testing is some of the most exciting work we do. As a premier cGMP contract service laboratory, PTL partners with pharmaceutical scientists to identify...
Beauty / Cosmetics Testing PTL’s analytical staff has years of experience designing test methods and performing analysis for cosmetic, skin care, fragrance and personal hygiene samples. Whether your company needs a third...